Do you mean save files or game installation files?
Is your game a download or CD version?
Game and save location can vary with the publisher.
The game and its saves are probably in the same location in Windows 10 that they'd be in Vista/7/8. The install and save locations might vary according to where the game is from and what version it is, but probably not because it is Windows 10.
An old download of the GOG version (April 2013) put the saves in
C:\Users\<your-username>\AppData\Local\VirtualStore\Program Files (x86)\GOG.com\The 7th Guest
The GOG version is apparently using ScummVM for the game rather than DOSBox.
That means saves will not be compatible with the original game.