Hi there, Flavor and
WELCOME TO GAMEBOOMERS! Boy, that's a toughie isn't it!?
There is no one solution, because the configuration is generated randomly. Here's some tips below that might help, from the walkthrough:
WARNING SPOILER:
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When one of the corner squares is clicked the three squares adjacent to it in the shape of a square flip from one picture to the next. Click on the square in the centre of the sides and all three squares on that side change. Clicking on the centre square flips the horizontally and vertically adjacent squares. The painting changes from the human Stauf to a Red Devil then to a Green Demon then back to the human Stauf.