Hi Andy's Mom and WELCOME TO GB
By picture do you mean the photograph or the painting?
The photograph is not needed to finish the game to any of it's endings - but is a fun side task. You need the prayer card from the reverand to trade for the photo. I think that some of these side quests are only available at certain parts of the game and before you move closer to the end portion.
If you mean the paintin (I am not clear where you are within the game) You have to know that a baby is being sought and have down all the things required to figure out true paternity. Then you trade proof of that for the baby and then trade the baby for the painting.
The cogarettes I am not sure I recall - I'll have to check on that.
Hope this helps