Dreamfall Chapters is at the top of my list for sure. Episode one exceeded all of my expectations (which were already extremely high), and I'm looking forward to the remaining episodes. This is the best game I've played since the original TLJ and will go on my list as one of my all time favorite games.
(Perhaps even my favorite, but that remains to be seen, as all episodes have to be out before I decide that.
)
Blackenrock is a very strong second on my list. Can't wait to continue The Lost Crown series.
The Downfall remake is also strong on my list, as I loved The Cat Lady and can't wait to see more from Harvester Games.
Also way up there are Martin Ganteföhr and Pendulo Studio's new Daedalic games, though I may have to wait for 2016 for those, so I'm holding off on a bit of enthusiasm for now.
I am also very much looking forward to these games:
Grim Fandango remake (Would be higher, but I've already played the original. One of my favorite games.
)
The Devil's Men
Silence: The Whispered World 2
Tales From the Borderlands (remaining episodes)
Game of Thrones (remaining episodes)
Syberia 3
Broken Age (part 2)
The Book of Unwritten Tales 2 (last part)
Lost Horizon 2 (if released this year)
Monolith
Life is Strange (though I am waiting for a bit more info on this one regarding DRM)
There may even be more that I'm forgetting! All in all, this looks to be one of the best years for games that I've seen in a long time.
EDIT: Forgot about King's Quest until I saw it on mbday630's list! As long as it turns out to be (at least mostly) an adventure game, that's on my list for sure as well.
EDIT 2: Also forgot about The Day of the Tentacle remake.