Culpa Innata! It's really a shame that we'll probably never see the sequel, as I think that Culpa should have become a series.
The side story was obviously headed toward something even bigger, and it's a shame that it will never be continued.
I definitely agree regarding Gabriel Knight 4 (and 5, 6 and so on
). Maybe that will happen one day since Sierra has been resurrected. I keep hoping, although it looks like Jane Jensen has moved away from games for the time being.
More Cognition would also be nice.
At least there's the new King's Quest to look forward to. I wasn't sure at first since the preview made it look action oriented, but based on what I've seen since, it actually looks really promising.