I have McAfee...and outside of that one event, when it auto-updated and quarantined all my newer Big Fish games (subsequently fixed by BFG contacting McAfee), I haven't had an issue. Also you can configure McAfee so that it doesn't automatically delete things. Mine prompts me or quarantines without deleting.
Quite frankly, both Norton and McAfee can become "overly protective" at times. I use McAfee because the suite is free from my ISP so the only price I pay is the occasional annoyance.