I love the Mystery Case File games! I have also enjoyed (and spent mucho time on) Luxor and Jewel Quest 1 and 2. And I am really looking forward to playing Fairy Godmother Tycoon (I ordered the boxed version after having played the one-hour demo and loved it).
I've got many others here too; Super Collapse 3, Inspector Parker, Bejeweled 2, Galapago, Westward, Diner Dash, Big Kahuna Reef, Mah Jong Quest, and the list goes on!! I'm very enthusiastic about many of them.