I just reinstalled 80 Days on my Win 7 and tried the "game.exe" switch. It didn't work for me, even trying different compatibilities. I got a white screen, the sound of the splash screen loading with no visuals, and then nothing. I'll fiddle around with it some more. Bah!
(I think the problem is that my OS is 64-bit and the game as it is only supports Runtime for 32-bit.)
"Bleat, Watson -- unmitigated bleat!" ~ Sherlock Holmes