It's actually Safecracker from 1997, not 2000.
It's a good game for puzzles, but it's best to play it on an old computer (from year 2000 or earlier) with Windows 98.
It has a problem with faster processors where the inventory list zips by too fast to select anything. There was a patch to correct the problem around the time XP came out, but computers kept getting faster and now even with the patch the inventory just zips by. You zip from the beginning of the inventory list to the end instead of scrolling.
Besides the problem with computer speed, there are things you must do prior to installing. For example, the game requires 3MB of memory, but if you have more than 1.5GB of memory, the game won't see any at all. So you have to reduce your virtual memory to an amount the game can see.
Inferno wrote up a "Setup Walkthrough" for installing Safecracker on XP, and some of what she wrote could be applied to newer versions of Windows.http://home.earthlink.net/~infernofilecabinet4/XpSetupsP_T/SC_Setup.htm
However you still have the speed problem to work out. (Computers are a lot faster than when Inferno wrote the walkthrough.) It's just a lot easier to run the game on an older, slower computer -- preferably a computer from around year 2000 or earlier (so you don't need the patch) and on Windows 95 or 98 (so you don't have to configure or run in compatibility mode).