Which version of Uru do you have?
There was more than one disc version.
Draclvr mentioned the Secdrv.sys issue and I have disabled it.
You'd have had to either
enable the secdrv.sys driver or use a NoCD. If you got a NoCD for a different version of the game, it won't work properly.
Your symptoms sound like either trigger functions (DRM deliberately messing up the game because it mistakenly detects the game as an illegal version) or a wrong version problem (which might be the problem if you used a NoCD).
Intel HD graphics is not the best for running games. But since the game used to run OK, the problem is probably related to DRM.
If you're able to play online, I'd recommend the free online game at
http://mystonline.com/en/Not only do you get everything in the original Myst Uru game plus To D'Ni and Path of the Shell, you get some additional Ages that weren't in any disc version. The online game also runs better with newer computers.