I have played both timelines, it is very much the same for both paths. If one plays the second timeline choosing Chapters instead of new one keeps all the perks accumulated and weapon upgrades (not the weapons, these will appear in time), it is in fact equivalent to game +.
It is important to watch, really to listen to, the end of the credits because one can hear a sound that clarifies the ending.
If real is what you can feel, smell, taste and see, then 'real' is simply electrical signals interpreted by your brain
From The Matrix