According to a recent post in EA forums
***here*** Avast antivirus might block it from starting.
with Avast acquiring AVG and the result taking effect with the 17 March 2017 update, Avast now has all the same problems AVG had when it came to running games. In effect: Avast will block Windows from properly accessing the registry (which causes random login and permission errors), and will make games fail to load due to timeouts and locked out files.
In short: The Origin Games folder needs to be excluded in Avast in order to play any games on Origin. It's quite frankly ridiculous, but hopefully with time they'll figure out how to make a program that protects you instead of preventing you from using the computer.