I am running Tex's Pandora Directive on a Windows 7 machine, and so far haven't had any problems. Now, though, the game locks up after a cut scene where Tex is gaining entry into the dorm. I can't get ride of the small icon that Tex was using, and no other control console button will respond. Is there a patch for this,or maybe I'm doing something in the wrong order? I'll try exploring elsewhere first, but if anyone happens to have seen this before I'd be grateful for some help.

You can try the patch Inferno has on her site -

TEX4.EXE

Rename your original TEX4.EXE to TEX4.org and replace it with the new file. Not sure what issues were addressed, so I can't say for sure it will help.