to GameBoomers katheo.
All of the Nancy Drew games run on Windows 10. Not sure what the problem is, but I would suggest that your friend start with these instructions
here - which talk about how to install ND games on Windows 10.
If for some reason your friend continues to have issues after that, I would recommend downloading the game from GOG
here for $5.99. The page says the game works with Windows 7/8/10/11.