I haven't played it, Giovanna, but this is from the walkthrough if you haven't already checked it:
Create all of the Zodiac signs printed on Pandora's Box by clicking the swirling symbols with the hand icon.
You can move the box itself with the arrows to see all the different symbols and use them as reference points. Click the swirling circles to create four different parts of each picture. If you make a mistake in one area, you can keep clicking that particular circle until you get it right. Once you have three pieces of a symbol matched up, however, you will only have three of four guesses to choose the last piece of the image.
Members have mentioned in other threads that this is a difficult puzzle, so I can only wish you

with it.